I recently performed a method count of all of the dependencies I am using. Of course Google Play Services is the worst offender. Far in second place is Couchbase Lite. As it turns out CBL itself is reasonable at 2261 methods. But it appears that CBL has a dependency on FasterXML/Jackson which comes in at 9091 methods. The two together equal about 17% of your allowable 65k methods for an Android app.
A quick search reveals that Gson is now faster and only has about 1200 methods. Any chance of moving CBL to the smaller, faster library?