Thanks @matthew for the quick reply, as I said at the opening post:
If it helps here is all of the specs:
I’m currently running my dev WildFly server locally under Windows 8.1 with JDK and JRE 1.8.0._40 x64 and Couchbase server is running remotely under Ubuntu Server 14.04 LTS.
I access the server through a VPN with under 5 ms of latency, so I dont belive VPN might be the issue. I’ve been accessing in the past MySQL servers with Java MySQL connector with the exact same setup without an issue, and although Couchbase is not the same It removes most doubts about the VPN causing any issue.
I also use NetBeans 8.0.2 as my default IDE not very relevant but you never know. 
Since the error is a NoClassDefFoundError I’m inclined to believe it might be an initialization error or as the name states an issue with the classpath, likely caused by WildFly using also netty, although it should be safe since they have separated namespaces.
Hope this helps.