@daschl Please see ^ and provide guidance
Found this: Java client don't connect another cluster node when first is down which links https://issues.couchbase.com/browse/JCBC-999
I don’t know if that will fix our current issue. We’re going to also try going back to 2.2.5 to see if this issue happens with that version. This is an app that was recently updated from 1.4.x to 2.2.5 that started exhibiting this behavior.