Here’s a pet project using PouchDB and Sync Gateway.
Check out the config file: https://github.com/jamiltz/GrowthHackersReader/blob/master/server/sync-gateway.json
So in your proj, you can just add the CORS setting with the domain you’re serving your web app from.
Please keep in mind this is experimental and you should use the nightly build of PouchDB and latest from master on Sync Gateway. Hope this helps, let us know how it works for you.