Which logs are safe to delete while server running?


I’m trying to clear some space on our production server and I can see that the couchbase logs directory is a couple GBs. All the files in it end with .#, where # is anything from 1-20 (e.g. couchdb.5), and there are a few files called memcached.log.#.txt. Is it safe for me to delete any of these files while the server is running?